Description

Methyl 5-Bromo-3-Nitrothiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromo and nitro substituents on the thiophene core, enabling precise molecular construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Acts as a monomer or functionalizing agent in the development of conductive polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution due to its reactive halogen site.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	Methyl 5-Bromo-3-Nitrothiophene-2-Carboxylate
CAS No.	99839-45-9
Molecular Formula	C7H4BrNO4S
Molecular Weight	278.08 g/mol
Synonyms	5-Bromo-3-nitrothiophene-2-carboxylic acid methyl ester; Methyl 5-bromo-3-nitro-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-bromo-3-nitro-, methyl ester; 5-Bromo-3-nitro-2-thiophenecarboxylic acid methyl ester; 99839-45-9; Methyl 5-bromo-3-nitrothiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-3-Nitrothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.