Description

2H-Pyrazino[2,1-A]Isoquinoline,1,3,4,6,7,11B-Hexahydro-,(R)-(9Ci) is a high-purity chiral organic compound, identified by CAS No. 99780-88-8, that serves as a sophisticated building block in advanced chemical synthesis. Its value lies in its complex, fused heterocyclic structure, which provides a versatile scaffold for creating novel molecules with specific stereochemistry. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and explore structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex heterocyclic core for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective catalytic reactions.
• Organic Electronic Materials Research: Investigated as a potential component in the development of organic semiconductors due to its conjugated polycyclic structure.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in heterocyclic and medicinal chemistry.
• Fine Chemical Synthesis: Acts as a specialized intermediate for creating complex, high-value fine chemicals and flavors/fragrances.

Basic Information

Product Name	2H-Pyrazino[2,1-A]Isoquinoline,1,3,4,6,7,11B-Hexahydro-,(R)-(9Ci)
CAS No.	99780-88-8
Molecular Formula	C12H14N2
Molecular Weight	186.26 g/mol
Synonyms	(R)-1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline; (R)-Hexahydropyrazinoisoquinoline; (R)-HPIQ; (R)-2H-Pyrazino[2,1-a]isoquinoline, 1,3,4,6,7,11b-hexahydro-; (R)-Cyclazine derivative; 99780-88-8; (R)-enantiomer of HPQ
EINECS	Contact for details

Quality Control

Our 2H-Pyrazino[2,1-A]Isoquinoline,1,3,4,6,7,11B-Hexahydro-,(R)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.