Description

5-Phenyl-3-Thiophenecarboxylic Acid is a high-purity organic building block featuring a thiophene core substituted with a phenyl ring and a carboxylic acid functional group. This compound matters as a versatile and critical intermediate for advanced organic synthesis, enabling the construction of complex molecules with tailored electronic and structural properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand synthesis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or inflammation.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Organic Electronic Materials: Acts as a building block for π-conjugated systems in the development of organic semiconductors, OLEDs, and sensors.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies, including cross-coupling reactions and heterocyclic chemistry.
• Fine Chemical Production: Integrated into multi-step synthesis pathways for producing specialty chemicals and advanced intermediates.

Basic Information

Item	Details
Product Name	5-Phenyl-3-Thiophenecarboxylic Acid
CAS No.	99578-58-2
Molecular Formula	C11H8O2S
Molecular Weight	204.24 g/mol
Synonyms	3-Thiophenecarboxylic acid, 5-phenyl-; 5-Phenylthiophene-3-carboxylic acid; 3-Carboxy-5-phenylthiophene; 5-Phenyl-3-thiophenecarboxylic acid; 5-Phenylthiophene-3-carboxylic acid; 99578-58-2 (CAS); 5-Phenyl-3-thienoic acid
EINECS	Contact for details

Quality Control

Our 5-Phenyl-3-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.