Description

Malonic Acid (1,3-13C2) is a stable isotope-labeled analog of malonic acid, where two carbon atoms at the 1 and 3 positions are replaced with the 13C isotope. This product is essential for advanced analytical research, providing a critical internal standard for quantitative mass spectrometry and enabling precise metabolic pathway tracing in NMR studies. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and agrochemical companies developing new active ingredients.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of malonic acid and related metabolites in biological samples via LC-MS or GC-MS.
• For NMR spectroscopy studies in biochemistry and medicinal chemistry to elucidate reaction mechanisms and metabolic flux analysis.
• In the synthesis of 13C-labeled complex molecules, intermediates, and active pharmaceutical ingredients (APIs) for drug discovery and development.
• Use in clinical research and diagnostics for developing advanced assays to study metabolic disorders.
• As a tracer in environmental science research to study the degradation pathways of organic compounds.
• For quality control and method validation in analytical laboratories to ensure accuracy and compliance with regulatory standards.

Basic Information

Product Name	Malonic Acid (1,3-13C2)
CAS No.	99524-14-8
Molecular Formula	13C2H4O4
Molecular Weight	106.05 g/mol
Synonyms	1,3-13C2-Malonic Acid; Propanedioic-1,3-13C2 Acid; 13C2-Labeled Malonic Acid; Isotopic Malonic Acid; Dicarboxylic-13C2 Acid; Methanedicarboxylic-1,3-13C2 Acid; (1,3-13C)Malonic Acid
EINECS	Contact for details

Quality Control

Our Malonic Acid (1,3-13C2) is manufactured under strict quality systems to ensure high isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to relevant industry standards for stable isotope-labeled compounds, ensuring reliable and reproducible performance in your sensitive analytical methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (chemical purity)
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.