Description

Acetyl Chloride-1-13C is a stable isotope-labeled derivative of acetyl chloride, where the carbonyl carbon is enriched with the 13C isotope. This compound is a critical reagent for the synthesis of 13C-labeled compounds, enabling precise tracking and quantification in metabolic and pharmacokinetic studies. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity isotopic building blocks for analytical and synthetic applications.

Application

• Pharmaceutical Research & Development: Key precursor for synthesizing 13C-labeled active pharmaceutical ingredients (APIs) and intermediates for use in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and clinical trials.
• Metabolomics & Biomedical Analysis: Used to prepare internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS), enhancing the accuracy and reliability of quantitative metabolic profiling.
• Agrochemical Development: Employed in the synthesis of isotopically labeled pesticides, herbicides, and their metabolites to study environmental fate, degradation pathways, and residue analysis.
• Organic Synthesis & Chemical Research: A versatile acylating agent for introducing the 13C-labeled acetyl group into a wide range of organic molecules, including esters, amides, and ketones, for mechanistic and synthetic studies.
• Material Science: Potential use in the synthesis of 13C-labeled polymers or advanced materials where isotopic labeling is used to study polymer dynamics, structure, and properties.
• NMR Spectroscopy: Serves as a starting material for preparing 13C-enriched compounds used as probes or standards in Nuclear Magnetic Resonance (NMR) spectroscopy to simplify spectra and gain detailed structural insights.

Basic Information

Product Name	Acetyl Chloride-1-13C
CAS No.	1520-57-6
Molecular Formula	C13CH3ClO
Molecular Weight	79.48 g/mol
Synonyms	Acetic-1-13C chloride; [1-13C]Acetyl chloride; Ethanoyl-1-13C chloride; 13C-Labeled acetyl chloride; (1-13C)Acetyl chloride; Carbon-13 labeled acetyl chloride; Isotopic acetyl chloride; [13C]Acetyl chloride
EINECS	Contact for details

Quality Control

Our Acetyl Chloride-1-13C is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of research and regulated industries. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment, chemical purity, and impurity profile. We adhere to rigorous quality standards and can provide material tailored to specific customer specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this product should be stored in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and strong bases. Containers must be kept tightly sealed under an inert atmosphere to prevent decomposition from moisture absorption.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.