Description

Acetic Acid-D4 CAS NO 1186-52-3 is a deuterated isotopologue of acetic acid, where all four hydrogen atoms are replaced by deuterium. This high-purity labeled compound is essential as an internal standard and tracer in quantitative analytical techniques, ensuring precise and accurate measurements. It is a critical reagent for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• NMR Spectroscopy: Used as a deuterated solvent for proton NMR, providing a non-interfering signal for structural analysis of organic compounds.
• Mass Spectrometry (MS): Serves as a crucial internal standard for the accurate quantification of acetic acid and related compounds in complex matrices via GC-MS or LC-MS.
• Metabolic Pathway Tracing: Employed in deuterium labeling studies to investigate biochemical mechanisms and metabolic fluxes in biological systems.
• Pharmaceutical Research: Utilized in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Polymer Science: Acts as a probe in the study of polymerization mechanisms and the analysis of polymer microstructure.
• Chemical Synthesis: Functions as a deuterium source or a labeled building block for the synthesis of more complex deuterated compounds.

Basic Information

Product Name	Acetic Acid-D4
CAS No.	1186-52-3
Molecular Formula	C₂D₄O₂
Molecular Weight	64.08 g/mol
Synonyms	Deuteroacetic Acid-d4; Acetic-d4 Acid; Perdeuteroacetic Acid; [2H4]Acetic Acid; Deuterated Acetic Acid (D, 99%); Ethanoic-d4 Acid; Glacial Acetic Acid-d4; CD3COOD
EINECS	214-693-1

Quality Control

Our Acetic Acid-D4 is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically D, 99%+), chemical purity, and relevant spectroscopic data. We adhere to cGMP principles where applicable to guarantee supply consistency and traceability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, ensure containers are sealed and stored upright away from heat, sparks, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to reference spectrum
Isotopic Purity (D)	≥ 99%
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%
NMR Solvent Suitability	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.