Description

(S)-1-[4-(Trifluoromethyl)Phenyl]Ethanol is a high-value chiral intermediate characterized by its single enantiomeric purity and a trifluoromethylphenyl group. This compound matters for its role in synthesizing advanced pharmaceutical and agrochemical agents, where its specific stereochemistry and fluorine substitution are critical for biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling highly selective synthetic transformations.
• Material Science Research: Employed in the development of specialty monomers for advanced polymers with unique optical or electronic properties.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in chiral separation techniques like HPLC.

Basic Information

Product Name	(S)-1-[4-(Trifluoromethyl)Phenyl]Ethanol
CAS No.	99493-93-3
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	(S)-1-[4-(Trifluoromethyl)phenyl]ethanol; (S)-α-(Trifluoromethyl)benzyl alcohol; (S)-1-(4-Trifluoromethylphenyl)ethanol; (S)-4-(Trifluoromethyl)benzyl alcohol; (S)-α-Methyl-4-(trifluoromethyl)benzenemethanol; (S)-1-(4-(Trifluoromethyl)phenyl)ethan-1-ol; (S)-F3C-Ph-CH(OH)CH3
EINECS	Contact for details

Quality Control

Our (S)-1-[4-(Trifluoromethyl)Phenyl]Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.