Description

2-(2,3-Dihydro-1H-Indol-7-Yl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is a specialized fluorinated indole derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a heterocyclic indoline moiety with a highly fluorinated propanol group, enabling precise modifications to target properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity, stability, and metabolic profile.
• Material Science Research: Serves as a precursor for fluorinated polymers or liquid crystals, contributing to materials with unique surface properties, chemical resistance, or optical characteristics.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological systems, leveraging the distinct properties of the fluorine label.
• Organic Electronics: Investigated as a component in the synthesis of organic semiconductors or charge-transport materials due to the electron-withdrawing nature of the hexafluoroisopropanol group.

Basic Information

Item	Details
Product Name	2-(2,3-Dihydro-1H-Indol-7-Yl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol
CAS No.	99483-01-9
Molecular Formula	C11H9F6NO
Molecular Weight	285.19 g/mol
Synonyms	7-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1H-indole; 2-(2,3-Dihydro-1H-indol-7-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol; 7-(Hexafluoro-2-hydroxyisopropyl)-2,3-dihydroindole; 2,3-Dihydro-7-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)-1H-indole; 7-(1,1,1,3,3,3-Hexafluoro-2-hydroxy-2-propyl)indoline; 99483-01-9; HFIP-Indoline derivative
EINECS	Contact for details

Quality Control

Our 2-(2,3-Dihydro-1H-Indol-7-Yl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO standards for research and development materials, ensuring reliable quality for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.