Description

1-Methyl-6-Nitro-1H-Indole is a specialized nitro-substituted indole derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the biological activity of the indole scaffold.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to its electron-accepting nitro group.
• Dye and Pigment Industry: Acts as an intermediate in the production of specialized dyes and pigments, where the indole structure contributes to color fastness and unique chromophoric properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including palladium-catalyzed cross-coupling reactions and nitro group manipulations.

Basic Information

Product Name	1-Methyl-6-Nitro-1H-Indole
CAS No.	99459-48-0
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	6-Nitro-1-methylindole; 1-Methyl-6-nitroindole; 1H-Indole, 1-methyl-6-nitro-; 6-Nitro-1-methyl-1H-indole; 99459-48-0; 1-Methyl-6-nitro-1H-indole
EINECS	Contact for details

Quality Control

Our 1-Methyl-6-Nitro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.