Description

Isopropyl 2,2,2-Trichloroacetimidate (Wxg01431) is a versatile and highly reactive chemical building block primarily used as a glycosylation promoter and a key reagent in organic synthesis. Its core value lies in its ability to efficiently activate alcohols for nucleophilic substitution, enabling the synthesis of complex molecules with high selectivity and yield. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and high-purity intermediates for advanced synthesis.

Application

• Glycosylation Reactions: A critical promoter for the synthesis of glycosides, oligosaccharides, and complex carbohydrates in pharmaceutical and biochemical research.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and other bioactive molecules.
• Agrochemical Synthesis: Serves as a key reagent in the production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Manufacturing: Employed in the preparation of specialty chemicals, flavors, fragrances, and advanced material precursors.
• Protecting Group Chemistry: Facilitates the selective protection and deprotection of hydroxyl groups in multi-step synthetic pathways.
• Academic & R&D: A valuable tool in university and corporate research laboratories for developing new synthetic methodologies.

Basic Information

Product Name	Isopropyl 2,2,2-Trichloroacetimidate (Wxg01431)
CAS No.	99418-52-7
Molecular Formula	C5H8Cl3NO
Molecular Weight	204.48 g/mol
Synonyms	2,2,2-Trichloroacetimidic Acid Isopropyl Ester; Isopropyl Trichloroacetimidate; Trichloroacetimidic Acid Isopropyl Ester; (Isopropoxy)(trichloromethyl)carbene?; Wxg01431; Glycosylation Promoter; Trichloroacetimidate Ester
EINECS	Contact for details

Quality Control

Our Isopropyl 2,2,2-Trichloroacetimidate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.