Description

Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-β-L-Fucopyranoside is a sophisticated, benzyl-protected thioglycoside derivative of L-fucose, a crucial deoxy sugar. This compound serves as a vital key synthetic intermediate and glycosyl donor in the stereoselective construction of complex oligosaccharides and glycoconjugates. It is primarily required by pharmaceutical researchers, process chemists, and biotechnology firms engaged in carbohydrate chemistry, glycobiology, and the development of novel therapeutics and diagnostic agents.

Application

• Glycosylation Reactions: Acts as a key glycosyl donor in the synthesis of fucose-containing oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Critical building block for the research and development of carbohydrate-based drugs, including selectin inhibitors and anti-inflammatory agents.
• Glycobiology Research: Used in studies of fucosylation processes, cell-cell recognition, and immune response modulation.
• Glycochip & Diagnostic Development: Employed in the creation of carbohydrate arrays and biosensors for pathogen detection and biomarker studies.
• Enzyme Substrate & Inhibitor Synthesis: Serves as a precursor for developing substrates or inhibitors for fucosyltransferases and other glycosyl-processing enzymes.
• Complex Natural Product Synthesis: Integral to the total synthesis of natural products containing fucose moieties.

Basic Information

Product Name	Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-β-L-Fucopyranoside
CAS No.	99409-34-4
Molecular Formula	C29H34O4S
Molecular Weight	478.64 g/mol
Synonyms	Ethyl 2,3,4-Tri-O-benzyl-1-thio-β-L-fucopyranoside; 1-Thioethyl 2,3,4-tri-O-benzyl-β-L-fucopyranoside; Ethyl 1-Thio-β-L-fucopyranoside 2,3,4-Tribenzyl Ether; β-L-Fucopyranoside, ethyl 2,3,4-tris-O-(phenylmethyl)-1-thio-; Ethyl 2,3,4-Tri-O-benzyl-1-thio-β-L-fucoside; 1-S-Ethyl 2,3,4-tri-O-benzyl-1-thio-β-L-fucopyranoside
EINECS	Contact for details

Quality Control

Our high-purity thioglycoside intermediates are manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label or COA. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.