Description

(R)-Orciprenaline is the single enantiomer form of the β-2 adrenergic receptor agonist orciprenaline, distinguished by its specific (R)-configuration. This high-purity chiral intermediate is critical for pharmaceutical research and development, particularly in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) targeting respiratory conditions. It is essential for manufacturers and research institutions focused on developing advanced bronchodilators and studying stereoselective drug action.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of enantiopure bronchodilator APIs.
• Research Chemical: Used in pharmacological studies to investigate the stereospecific activity of β-2 adrenergic agonists.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Process Development: Employed in the development and optimization of asymmetric synthesis routes.
• Metabolite Studies: Utilized in the research of drug metabolism and pharmacokinetics (DMPK) for respiratory therapeutics.

Basic Information

Product Name	(R)-Orciprenaline
CAS No.	99396-41-5
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	(R)-Metaproterenol; (R)-Alotak; (R)-1-(3,5-Dihydroxyphenyl)-2-isopropylaminoethanol; (R)-α-((Isopropylamino)methyl)-3,5-dihydroxybenzyl alcohol; (R)-3,5-Dihydroxy-α-((isopropylamino)methyl)benzyl alcohol; (R)-Orciprenaline sulfate (salt form); (-)-Orciprenaline
EINECS	Contact for details

Quality Control

Our (R)-Orciprenaline is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.