Description

7,8-Didehydro-4,5α-Epoxy-14-Hydroxy-3-Methoxy-17-Propylmorphinan-6-One is a high-purity, specialized morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of novel opioid receptor ligands. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuropharmacology, medicinal chemistry, and controlled substance analysis.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic building block in the research and development of new analgesic and neuroactive pharmaceutical compounds.
• Reference Standard: Used as a high-purity calibration standard in analytical laboratories for method development and quality control testing of related substances.
• Medicinal Chemistry Research: A vital tool for structure-activity relationship (SAR) studies to understand and modulate opioid receptor interactions.
• Forensic Analysis: Employed as a certified reference material (CRM) for the accurate identification and quantification of controlled substances in forensic toxicology.
• Biochemical Research: Utilized in in-vitro studies to investigate binding affinities and pharmacological profiles at specific receptor sites.
• Process Development: Acts as a critical intermediate during the scale-up and optimization of synthetic routes for target active pharmaceutical ingredients (APIs).

Basic Information

Product Name	7,8-Didehydro-4,5α-Epoxy-14-Hydroxy-3-Methoxy-17-Propylmorphinan-6-One
CAS No.	99307-36-5
Molecular Formula	C22H27NO5
Molecular Weight	385.46 g/mol
Synonyms	17-Propyl-4,5α-epoxy-3,14-dihydroxy-6-oxomorphinan; 17-Propylmorphinan-6-one derivative; 14-Hydroxy-3-methoxy-17-propylmorphinan-6-one; 4,5α-Epoxy-14-hydroxy-3-methoxy-17-propylmorphinan-6-one; 7,8-Didehydromorphinan derivative; Propylmorphinanone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 7,8-Didehydro-4,5α-Epoxy-14-Hydroxy-3-Methoxy-17-Propylmorphinan-6-One is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.