Description

1-(2,3-Dihydro-3-Hydroxy-1H-Indol-1-Yl)-Ethanone is a specialized indole derivative, a key heterocyclic building block prized for its functional group versatility. This compound is critical for researchers and manufacturers requiring a high-purity intermediate with a reactive ketone and a protected hydroxyl group on the indoline scaffold. It is primarily utilized in the synthesis of complex pharmaceutical agents, agrochemicals, and advanced organic materials where precise molecular architecture is essential.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the indole core's bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or emissive layer materials in display and lighting technologies.
• Fine Chemical and Dye Manufacturing: Employed in the production of specialized dyes, pigments, and complex fragrance compounds.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.
• Ligand and Catalyst Development: Used to construct sophisticated chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-(2,3-Dihydro-3-Hydroxy-1H-Indol-1-Yl)-Ethanone
CAS No.	99293-86-4
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	1-Acetyl-3-hydroxyindoline; 3-Hydroxy-1-acetylindoline; 3-Hydroxyindoline-1-acetone; N-Acetyl-3-hydroxyindoline; 1-Acetyl-3-hydroxy-2,3-dihydro-1H-indole; Ethanone, 1-(3-hydroxy-2,3-dihydro-1H-indol-1-yl)-; 3-Hydroxy-1H-indole-1-acetic acid methylene ketone
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dihydro-3-Hydroxy-1H-Indol-1-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.