Description

1-Mercapto-2,2-Di-(Isopropoxycarbonyl)Ethenyl-1-Thioglucosiduronic Acid is a specialized thioglucuronide derivative, a key building block in advanced organic synthesis. Its complex structure, featuring both mercapto and glucuronic acid moieties, makes it a valuable intermediate for creating novel compounds with targeted biological activity. This high-purity chemical is essential for research and development in pharmaceutical chemistry, particularly in the design of prodrugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those designed for targeted delivery or specific metabolic pathways.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive thiol and carboxylate groups.
• Prodrug Synthesis: Serves as a key component for constructing prodrugs that utilize glucuronidation for site-specific activation.
• Enzyme Inhibitor Research: Employed in the development of inhibitors targeting glycosidases and other carbohydrate-processing enzymes.
• Biochemical Research: Used as a substrate or inhibitor in studies of glucuronosyltransferase enzymes and related metabolic processes.
• Specialty Chemical Synthesis: Acts as a sophisticated building block for creating complex molecules in agrochemical and material science research.

Basic Information

Product Name	1-Mercapto-2,2-Di-(Isopropoxycarbonyl)Ethenyl-1-Thioglucosiduronic Acid
CAS No.	99290-96-7
Molecular Formula	C₁₇H₂₄O₁₀S₂
Molecular Weight	452.50 g/mol
Synonyms	1-Thio-β-D-glucopyranosiduronic acid, 1-[1-mercapto-2,2-bis(1-methylethoxycarbonyl)ethenyl]-; 1-Mercapto-2,2-diisopropoxycarbonylvinyl 1-thio-β-D-glucopyranosiduronic acid; Thioglucuronide derivative CAS 99290-96-7; (Isopropoxycarbonyl)Ethenyl Thioglucosiduronic Acid; Advanced thioglucuronide synthon
EINECS	Contact for details

Quality Control

Our 1-Mercapto-2,2-Di-(Isopropoxycarbonyl)Ethenyl-1-Thioglucosiduronic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.