Description

tert-Butyl 2-Iodo-5-Methoxy-1H-Indole-1-Carboxylate is a high-value, multi-functional indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected, reactive scaffold for constructing complex heterocyclic molecules, enabling precise structural modifications. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or precursor for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and molecular probes for biological target identification.
• Academic & R&D: Fundamental reagent in methodological organic synthesis and heterocyclic chemistry research.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs for client-specific molecule assembly.

Basic Information

Product Name	tert-Butyl 2-Iodo-5-Methoxy-1H-Indole-1-Carboxylate
CAS No.	99275-48-6
Molecular Formula	C14H16INO3
Molecular Weight	373.19 g/mol
Synonyms	1-Boc-2-iodo-5-methoxyindole; 2-Iodo-5-methoxy-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2-iodo-5-methoxyindole-1-carboxylate; 5-Methoxy-2-iodo-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-iodo-5-methoxyindole; Boc-2-I-5-MeO-indole; 99275-48-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Iodo-5-Methoxy-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.