Description

2-Iodo-n-(tert-Butoxycarbonyl)Indole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex heterocyclic frameworks, particularly in the development of pharmaceuticals and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated indole core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological studies in cross-coupling reactions (e.g., Suzuki, Sonogashira) and indole functionalization chemistry.
• Peptidomimetics & Bioconjugation: The Boc-protected amine allows for selective deprotection and further coupling, useful in designing peptide analogs and bioconjugates.

Basic Information

Product Name	2-Iodo-n-(tert-Butoxycarbonyl)Indole
CAS No.	99275-46-4
Molecular Formula	C₁₃H₁₄INO₂
Molecular Weight	359.16 g/mol
Synonyms	1-Boc-2-iodoindole; 2-Iodo-1-(tert-butoxycarbonyl)indole; tert-Butyl 2-iodo-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 2-iodo-, 1,1-dimethylethyl ester; N-Boc-2-iodoindole; 2-Iodoindole-1-carboxylic acid tert-butyl ester; Boc-2-I-indole
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-n-(tert-Butoxycarbonyl)Indole is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.