Description

3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-1-Oxo-,(S)-(9Ci) is a high-purity, chiral isoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical, structurally-defined building block for the development of novel pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and chemical manufacturers specializing in medicinal chemistry, process development, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing compound libraries in drug discovery programs to explore structure-activity relationships (SAR).
• Asymmetric Synthesis: Employed as a starting material or reagent in stereoselective synthesis due to its defined (S)-configuration, enabling the construction of enantiomerically pure compounds.
• Biochemical Research: Potential use as a substrate or inhibitor in enzymatic studies, given its specific amino and carboxylic acid functional groups on the tetrahydroisoquinoline core.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of complex fine chemicals and advanced materials.

Basic Information

Product Name	3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-1-Oxo-,(S)-(9Ci)
CAS No.	99206-27-6
Molecular Formula	C10H10N2O3
Molecular Weight	206.20 g/mol
Synonyms	(S)-7-Amino-1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid; 7-Amino-1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid, (S)-; 3-Isoquinolinecarboxylic acid, 7-amino-1,2,3,4-tetrahydro-1-oxo-, (S)-; (S)-7-Amino-3,4-dihydro-1-oxo-1H-isoquinoline-3-carboxylic acid; 99206-27-6; (S)-ATIQ; (S)-enantiomer of 7-Amino-1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxylicacid,7-Amino-1,2,3,4-Tetrahydro-1-Oxo-,(S)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.