Description

Ketone, Bicyclo[2.2.2]Oct-5-En-2-Yl Chloromethyl (6Ci) is a specialized bicyclic ketone derivative featuring a reactive chloromethyl group, making it a valuable and versatile building block in advanced organic synthesis. Its unique bridged-ring structure and functional handles are critical for constructing complex molecular architectures with specific steric and electronic properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and other bioactive molecules with complex ring systems.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its bicyclic framework can contribute to unique modes of action.
• Ligand and Catalyst Development: Acts as a starting material for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Employed as a functional monomer or cross-linking agent to introduce rigid, bicyclic units into polymer backbones, enhancing thermal and mechanical properties.
• Material Science Research: Utilized in the development of advanced organic electronic materials and liquid crystals due to its potential for fine-tuning molecular geometry and polarity.
• Chemical Biology Probes: Functions as a scaffold for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	Ketone, Bicyclo[2.2.2]Oct-5-En-2-Yl Chloromethyl (6Ci)
CAS No.	99187-89-0
Molecular Formula	C10H13ClO
Molecular Weight	184.66 g/mol
Synonyms	2-(Chloromethyl)bicyclo[2.2.2]oct-5-en-2-one; Bicyclo[2.2.2]oct-5-ene-2-carbaldehyde, 2-(chloromethyl)-; 2-(Chloromethyl)-2-oxobicyclo[2.2.2]oct-5-ene; 99187-89-0; (Chloromethyl)bicyclo[2.2.2]octenone; Bicyclo[2.2.2]oct-5-en-2-yl(chloromethyl) ketone
EINECS	Contact for details

Quality Control

Every batch of Ketone, Bicyclo[2.2.2]Oct-5-En-2-Yl Chloromethyl (6Ci) is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support custom purity grades to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloromethyl group and light-sensitive nature, it is recommended to store under an inert atmosphere for long-term stability and to minimize decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.