Description

(+/-)-4-[2-[[3-(4-Hydroxyphenyl)-1-Methylpropyl]Amino]-1-Hydroxyethyl]Phenol Hydrochloride is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its structural complexity and potential as a key building block in the synthesis of active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists working in the pharmaceutical and fine chemical industries. The material is supplied with rigorous quality control to ensure batch-to-batch consistency for critical synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development, validation, and impurity profiling of related drug substances.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the pharmacological profile of lead compounds targeting specific receptors.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant scale, focusing on yield optimization and impurity control.
• Academic Research: Applied in university and institutional labs for fundamental studies in organic synthesis and asymmetric catalysis.

Basic Information

Product Name	(+/-)-4-[2-[[3-(4-Hydroxyphenyl)-1-Methylpropyl]Amino]-1-Hydroxyethyl]Phenol Hydrochloride
CAS No.	99095-19-9
Molecular Formula	C19H25NO3·HCl
Molecular Weight	351.87 g/mol (free base: 315.41 g/mol)
Synonyms	4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]-1-hydroxyethyl]phenol hydrochloride; 1-(4-Hydroxyphenyl)-2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethanol hydrochloride; (±)-Denopamine Hydrochloride Impurity; Rac-Denopamine Hydrochloride; Denopamine Related Compound; 99095-19-9; 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]-1-hydroxyethyl]phenol monohydrochloride
EINECS	Contact for details

Quality Control

Our production of (+/-)-4-[2-[[3-(4-Hydroxyphenyl)-1-Methylpropyl]Amino]-1-Hydroxyethyl]Phenol Hydrochloride adheres to stringent internal quality standards designed for research and pharmaceutical intermediate applications. Each batch is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which may affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.