Description

3-Isoquinolinemethanol, 1,2,3,4-Tetrahydro-, Hydrochloride is a versatile heterocyclic building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its functionalized isoquinoline core, which serves as a key precursor for the development of complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of novel alkaloid analogs and other pharmacologically active compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) and the exploration of structure-activity relationships (SAR) in drug discovery programs.
• Alkaloid Synthesis: Serves as a key precursor for the construction of complex tetrahydroisoquinoline alkaloids and their derivatives.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and the synthesis of specialized fine chemicals.

Basic Information

Product Name	3-Isoquinolinemethanol, 1,2,3,4-Tetrahydro-, Hydrochloride
CAS No.	99074-98-3
Molecular Formula	C₁₀H₁₃NO·HCl
Molecular Weight	199.68 g/mol
Synonyms	1,2,3,4-Tetrahydro-3-isoquinolinemethanol hydrochloride; 3-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; Tetrahydroisoquinoline-3-methanol hydrochloride; 1,2,3,4-Tetrahydroisoquinoline-3-methanol HCl; 3-Hydroxymethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; (1,2,3,4-Tetrahydro-3-isoquinolinyl)methanol hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinemethanol, 1,2,3,4-Tetrahydro-, Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We offer material suitable for research and development purposes, with typical purity levels meeting the stringent requirements of pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA), detailing identity, purity, and impurity profiles, is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.