Description

7-((n-Tosylphenylalanyl)Amino)-4-Chloro-3-Methoxyisocoumarin is a specialized synthetic organic compound belonging to the isocoumarin class, designed as a potent and selective protease inhibitor. This high-purity biochemical is critical for advanced research and development in life sciences, enabling precise modulation of enzymatic activity. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on drug discovery and mechanistic enzymology studies.

Application

• Protease Inhibition Research: Serves as a key biochemical tool for studying serine protease mechanisms and kinetics in vitro.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays to identify and validate novel therapeutic targets related to protease activity.
• Biochemical Pathway Analysis: Enables the investigation of specific proteolytic pathways in cellular and molecular biology research.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Enzyme Characterization: Employed to determine inhibitor constants (Ki) and elucidate the structure-activity relationships (SAR) of protease inhibitors.

Basic Information

Product Name	7-((n-Tosylphenylalanyl)Amino)-4-Chloro-3-Methoxyisocoumarin
CAS No.	99033-29-1
Molecular Formula	C27H25ClN2O6S
Molecular Weight	541.02 g/mol
Synonyms	4-Chloro-3-methoxy-7-[[(2S)-2-[[(4-methylphenyl)sulfonyl]amino]-3-phenylpropanoyl]amino]-2H-1-benzopyran-2-one; 7-((N-Tosyl-L-phenylalanyl)Amino)-4-Chloro-3-Methoxyisocoumarin; Protease Inhibitor 99033-29-1; 4-Chloro-3-methoxyisocoumarin derivative; TPCK-related inhibitor; TLCH; Chymotrypsin-like protease inhibitor
EINECS	Contact for details

Quality Control

Our 7-((n-Tosylphenylalanyl)Amino)-4-Chloro-3-Methoxyisocoumarin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, keep desiccated under an inert atmosphere. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.