Description

tert-Butyl 2,2,2-Trichloroacetimidate is a specialized organic reagent widely used as a versatile protecting group and activating agent in synthetic chemistry. Its primary value lies in its ability to facilitate the formation of glycosidic bonds and other complex molecular linkages under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in advanced organic synthesis and process development.

Application

• Glycosylation Reactions: A key reagent for the efficient synthesis of oligosaccharides and complex carbohydrates.
• Pharmaceutical Intermediates: Used in the production of active pharmaceutical ingredients (APIs), particularly in nucleoside and antibiotic synthesis.
• Protecting Group Chemistry: Serves as a robust protecting group for hydroxyl functions during multi-step synthetic sequences.
• Agrochemical Synthesis: Employed in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Utilized in the synthesis of specialty chemicals, flavors, and fragrances requiring high-precision coupling steps.
• Academic & Process R&D: A critical tool for method development and scaling novel synthetic pathways in research laboratories.

Basic Information

Product Name	tert-Butyl 2,2,2-Trichloroacetimidate
CAS No.	98946-18-0
Molecular Formula	C6H10Cl3NO
Molecular Weight	218.51 g/mol
Synonyms	2,2,2-Trichloroacetimidic Acid tert-Butyl Ester; tert-Butyl Trichloroacetimidate; Trichloro-tert-butoxycarbeneamine; (Trichloroacetyl)imino-tert-butane; TBTA; TCAI-tBu; 1,1-Dimethylethyl 2,2,2-trichloroethanimidate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,2,2-Trichloroacetimidate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for research and commercial-scale chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and efficacy.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.