Description

4-(Acetyl-D3)-Bromobenzene is a deuterated aromatic ketone derivative, specifically a labeled analog of 4'-Bromoacetophenone, where three hydrogen atoms on the acetyl methyl group are replaced with deuterium. This isotopic labeling provides a stable, non-radioactive tracer essential for advanced analytical and research applications, offering distinct spectroscopic properties. It is a critical building block and internal standard for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise molecular tracking and quantification.

Application

• Pharmaceutical Research & Development: Serves as a key deuterated intermediate in the synthesis of labeled drug candidates for pharmacokinetic (ADME) studies, metabolic pathway tracing, and bioanalytical method development.
• Analytical Chemistry & Mass Spectrometry: Employed as a high-purity internal standard for the accurate quantification of 4'-Bromoacetophenone and related compounds via GC-MS or LC-MS, improving analytical precision and reliability.
• Metabolomics and Proteomics: Used in stable isotope labeling strategies to investigate biological pathways, protein turnover, and metabolite profiling in complex biological matrices.
• Agrochemical Development: Acts as a labeled precursor in the research and environmental fate studies of agrochemicals, helping to understand degradation pathways and environmental impact.
• Material Science Research: Utilized in the development of novel organic electronic materials and liquid crystals where deuterium substitution can fine-tune physical and electronic properties.
• NMR Spectroscopy Solvent & Reagent: Functions as a useful deuterated compound for NMR spectroscopy applications, aiding in structural elucidation and reaction monitoring.

Basic Information

Product Name	4-(Acetyl-D3)-Bromobenzene
CAS No.	98815-54-4
Molecular Formula	C8H4D3BrO
Molecular Weight	202.06 g/mol (approx.)
Synonyms	4'-Bromoacetophenone-d3; 1-(4-Bromophenyl)ethanone-d3; p-Bromoacetophenone-d3; 4-Acetyl-D3-bromobenzene; (4-Bromophenyl)(2H3)ethanone; 4-Bromo-D3-acetophenone; Deuterated 4'-Bromoacetophenone; Acetophenone-d3, 4'-bromo-
EINECS	Contact for details

Quality Control

Our 4-(Acetyl-D3)-Bromobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C) for structural confirmation and deuterium incorporation, and HPLC/GC for chemical and isotopic purity assessment. A detailed Certificate of Analysis (COA) is provided, documenting key specifications such as chemical purity, isotopic enrichment (D-atom %), and impurity profiles to ensure consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥98.0% (Chemical Purity)
Isotopic Purity (D-atom %)	≥98.0% (by MS or NMR)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.