Description

7-Methyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, synthetically derived tetrahydroisoquinoline derivative that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its value lies in its unique fused-ring structure, which is integral to the synthesis of bioactive molecules targeting the central nervous system. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially those with neurological activity.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds and natural product analogs due to its rigid tetrahydroisoquinoline scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) for preclinical evaluation.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to introduce stereochemical complexity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	7-Methyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	98698-22-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	7-Methyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 3-Carboxy-7-methyl-1,2,3,4-tetrahydroisoquinoline; 7-Methyl-THIQ-3-COOH; (R/S)-7-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Methyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; 7-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate; 7-Methyl-THIQ-3-CA
EINECS	Contact for details

Quality Control

Our 7-Methyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.