Description

(S)-(-)-2-Hydroxy-4-(2-Methoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaphosphorinane 2-Oxide is a high-purity, chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a versatile chiral auxiliary or ligand, enabling the stereoselective synthesis of complex molecules. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where precise control over molecular chirality is critical for creating active ingredients with the desired biological activity.

Application

• As a chiral ligand in asymmetric catalysis for the synthesis of enantiomerically pure pharmaceuticals.
• Utilized as a key chiral auxiliary in the stereocontrolled construction of complex natural products and bioactive molecules.
• Employed in methodological research for developing new asymmetric synthetic transformations.
• Potential use in the synthesis of chiral agrochemicals and fine chemicals requiring high enantiomeric purity.
• Acts as a building block or intermediate for novel organophosphorus compounds with specialized properties.
• Applied in academic and industrial R&D settings for exploring structure-activity relationships (SAR) in drug discovery.

Basic Information

Product Name	(S)-(-)-2-Hydroxy-4-(2-Methoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaphosphorinane 2-Oxide
CAS No.	98674-83-0
Molecular Formula	C₁₃H₁₉O₅P
Molecular Weight	286.26 g/mol
Synonyms	(S)-(-)-2-Hydroxy-4-(2-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide; (S)-2-Hydroxy-4-(2-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide; (S)-(-)-HMP; (S)-HMP; (S)-(-)-2-Hydroxy-4-(o-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide; (S)-(-)-2-Hydroxy-4-(2-methoxyphenyl)-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane; (S)-enantiomer of HMP ligand
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Hydroxy-4-(2-Methoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaphosphorinane 2-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.