Description

5-Fluoro-2-Methyl-1H-Indole-3-Carboxylic Acid is a high-purity, fluorinated indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique molecular scaffold enables precise structural modifications. Pharmaceutical researchers, agrochemical developers, and fine chemical manufacturers need this material for creating compounds with targeted biological activity, leveraging the fluorine atom's ability to modulate potency, metabolic stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functional unit in the creation of specialty polymers and advanced organic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry.
• Fluorinated Compound Library: A valuable component for building diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	5-Fluoro-2-Methyl-1H-Indole-3-Carboxylic Acid
CAS No.	98621-77-3
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	5-Fluoro-2-methylindole-3-carboxylic acid; 2-Methyl-5-fluoro-1H-indole-3-carboxylic acid; 5-Fluoro-2-methyl-1H-indole-3-carboxylic acid; 98621-77-3; 5-Fluoro-2-methylindole-3-carboxylate; 3-Carboxy-5-fluoro-2-methylindole; 5-Fluoro-2-methyl-3-indolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methyl-1H-Indole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.