Description

5-Amino-1-Benzothiophene-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key precursor in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its benzothiophene core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments due to its amino and carboxylic acid functional groups.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	5-Amino-1-Benzothiophene-2-Carboxylic Acid
CAS No.	98589-46-9
Molecular Formula	C9H7NO2S
Molecular Weight	193.22 g/mol
Synonyms	5-Amino-1-benzothiophene-2-carboxylic acid; 5-Amino-benzo[b]thiophene-2-carboxylic acid; 2-Carboxy-5-aminobenzo[b]thiophene; 5-Amino-2-benzothiophenecarboxylic acid; 98589-46-9; 5-Amino-1-benzothiophene-2-carboxylate; 5-Aminobenzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Benzothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.