Description

1H-Isoindole-1,3(2H)-Dione, 5-Iodo- is a halogenated isoindole-1,3-dione derivative, a versatile and high-value building block in advanced organic synthesis. Its core value lies in its iodine substituent, which provides a reactive handle for further functionalization via cross-coupling reactions, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with specific modes of action.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host materials in display and lighting technologies.
• Polymer Chemistry: Incorporated into polymer backbones to create specialty polyimides or polyamides with enhanced thermal stability and specific electronic properties.
• Cross-Coupling Reactions: The iodine atom acts as an excellent leaving group in palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings for carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized to synthesize novel chelating ligands for metal complexes used in catalysis.
• Fluorescent Probe Synthesis: A starting material for creating sensitive chemical sensors and bio-imaging agents.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 5-Iodo-
CAS No.	98556-60-6
Molecular Formula	C8H4INO2
Molecular Weight	273.03 g/mol
Synonyms	5-Iodoisoindoline-1,3-dione; 5-Iodophthalimide; 5-Iodo-1H-isoindole-1,3(2H)-dione; 5-Iodophthalic acid imide; 5-Iodo-2,3-dihydro-1H-isoindole-1,3-dione; 5-Iodoisoindoline-1,3-dione; 5-Iodo-1,3-dihydro-2H-isoindole-1,3-dione
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1,3(2H)-Dione, 5-Iodo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.