Description

3-Amino-4,5-Dimethylthiophene-2-Carboxylic Acid is a high-value heterocyclic building block featuring both amino and carboxylic acid functional groups on a substituted thiophene core. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and organic semiconductors used in OLEDs, sensors, and conductive materials.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized thiophene-based dyes and pigments for high-performance applications.
• Ligand & Catalyst Development: The amino and carboxyl groups make it a useful starting material for creating novel chelating ligands and organocatalysts.
• Academic & Contract Research: A valuable reagent for methodological studies and the discovery of new chemical reactions in university and CRO laboratories.

Basic Information

Product Name	3-Amino-4,5-Dimethylthiophene-2-Carboxylic Acid
CAS No.	98547-43-4
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	2-Carboxy-3-amino-4,5-dimethylthiophene; 4,5-Dimethyl-3-aminothiophene-2-carboxylic acid; 3-Amino-4,5-dimethyl-2-thiophenecarboxylic acid; 4,5-Dimethyl-3-aminothiophene-2-carboxylate; ADTC; 2-Thiophenecarboxylic acid, 3-amino-4,5-dimethyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. We adhere to strict in-house specifications and can provide supporting documentation, including detailed Certificates of Analysis (COA), upon request to meet the needs of cGMP, ISO, or other quality system environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.