Description

Linoleic Acid-1-13C is a stable isotope-labeled analog of linoleic acid, a key essential ω-6 fatty acid. This compound is crucial for metabolic and nutritional tracer studies, enabling precise tracking and quantification in complex biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutritional science, and biochemistry sectors for advanced analytical applications.

Application

• Metabolic Pathway Analysis: As an internal standard in mass spectrometry for studying fatty acid metabolism, β-oxidation, and lipid biosynthesis.
• Nutritional Research: Tracer studies to investigate the absorption, distribution, and biological effects of linoleic acid in dietary and clinical research.
• Pharmaceutical Development: Used in drug metabolism and pharmacokinetics (DMPK) studies for lipid-based drug formulations.
• Biochemical Assays: A critical reagent in enzymatic assays and in vitro studies involving desaturases and elongases.
• Quality Control & Reference Standard: Serves as a certified reference material (CRM) for the calibration and validation of analytical methods in quality control laboratories.

Basic Information

Product Name	Linoleic Acid-1-13C
CAS No.	98353-71-0
Molecular Formula	C18H32O2 (with 13C at position 1)
Molecular Weight	~281.4 g/mol
Synonyms	(9Z,12Z)-Octadeca-9,12-dienoic-1-13C acid; 13C-Linoleic Acid; Linoleic Acid (1-13C); Isotopically Labeled Linoleic Acid; 9,12-Linoleic Acid-1-13C; cis,cis-9,12-Octadecadienoic-1-13C Acid; [1-13C]-Linoleic Acid; 13C Labeled Linoleic Acid
EINECS	Contact for details

Quality Control

Our Linoleic Acid-1-13C is produced under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, typically exceeding 99% chemical purity and 99 atom % 13C. Certificates of Analysis (COA) detailing specific batch results for identity, purity (by GC or HPLC), isotopic enrichment (by NMR or MS), and related substances are provided. We adhere to relevant standards for research chemicals and can support cGMP requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the container sealed in a cool, dry, and well-ventilated area. Allow the product to reach room temperature in its sealed container before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity	≥ 99%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.