Description

Valine, 3-Mercapto-, Methyl Ester is a specialized amino acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both a thiol and an ester functional group, makes it a valuable precursor for constructing complex molecules with high stereochemical fidelity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications such as peptide mimetics, drug discovery, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, ACE inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of modified peptides and peptidomimetics, where the thiol group allows for specific conjugation or cyclization strategies.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Bioconjugation & Linker Chemistry: The reactive thiol and ester functionalities enable its use in creating custom linkers for antibody-drug conjugates (ADCs) and other bioconjugation platforms.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing sulfur-containing flavor compounds and aroma chemicals.
• Material Science: Investigated as a monomer or cross-linking agent for producing specialty polymers with unique properties.

Basic Information

Product Name	Valine, 3-Mercapto-, Methyl Ester
CAS No.	98278-24-1
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	L-Valine, 3-mercapto-, methyl ester; Methyl 3-mercapto-L-valinate; (2S)-2-Amino-3-mercapto-3-methylbutanoic acid methyl ester; 3-Mercapto-L-valine methyl ester; 3-Methyl-2-(methylamino)-3-sulfanylbutanoic acid methyl ester; 3-Thiavaline methyl ester; A thiol-containing valine derivative
EINECS	Contact for details

Quality Control

Our Valine, 3-Mercapto-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.