Description

(S)-(+)-3-Bromo-2-Methyl-1-Propanol CAS NO 98244-48-5 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in the presence of both a reactive bromine atom and a chiral alcohol functional group, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require enantiomerically pure intermediates for the development of active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Material Science Research: Acts as a monomer or modifying agent for creating chiral polymers and advanced materials with specific optical properties.

Basic Information

Item	Details
Product Name	(S)-(+)-3-Bromo-2-Methyl-1-Propanol
CAS No.	98244-48-5
Molecular Formula	C4H9BrO
Molecular Weight	153.02 g/mol
Synonyms	(S)-3-Bromo-2-methylpropan-1-ol; (S)-(+)-3-Bromo-2-methyl-1-propanol; (S)-3-Bromo-2-methylpropyl alcohol; (S)-2-Methyl-3-bromo-1-propanol; (+)-3-Bromo-2-methyl-1-propanol; (S)-Homoallylic alcohol bromide derivative; (S)-β-Bromoisobutyl alcohol
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-Bromo-2-Methyl-1-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high enantiomeric excess (e.e.) and chemical purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing specifications for identity, purity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and reactivity, it is recommended to handle under an inert atmosphere for extended storage periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.