Description

5-Chloro-1,3-Dihydroisobenzofuran-1-Ol is a versatile and high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its unique isobenzofuranol structure, which serves as a critical building block for creating complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

This specialized intermediate enables key synthetic pathways across several high-value industries. Its primary applications include:

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or building block for developing novel polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and as a ligand in catalytic systems.
• Fine Chemical Production: Integral to the manufacture of dyes, pigments, and other performance chemicals requiring precise chlorinated isobenzofuran structures.

Basic Information

Product Name	5-Chloro-1,3-Dihydroisobenzofuran-1-Ol
CAS No.	98216-82-1
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	5-Chloro-1-hydroxy-1,3-dihydroisobenzofuran; 5-Chloro-1,3-dihydroisobenzofuran-1-ol; 1,3-Dihydro-5-chloro-1-isobenzofuranol; 5-Chloro-1-hydroxyisobenzofuran; 98216-82-1; 5-Chloro-1,3-dihydro-2-benzofuran-1-ol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Our production of 5-Chloro-1,3-Dihydroisobenzofuran-1-Ol adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. Our quality systems are designed to meet the exacting standards of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.