Description

Trimethylsilyl(Trimethylsilyl)Propynoate is a specialized organosilicon reagent featuring a propynoate ester protected by two trimethylsilyl groups. This compound is valued for its dual functionality, serving as both a silylating agent and a protected acetylene derivative in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing acetylene and silyl-protected carboxylate functionalities into target molecules during drug discovery and development.
• Agrochemical Research: Used in the synthesis of novel active ingredients that require specific alkyne or silyl ester components for enhanced biological activity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, silicones, and functional coatings.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Heck) and as a protecting group for carboxylic acids in multi-step syntheses.
• Chemical Research & Development: A versatile tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating complex organic molecules.

Basic Information

Product Name	Trimethylsilyl(Trimethylsilyl)Propynoate
CAS No.	97927-35-0
Molecular Formula	C11H22O2Si2
Molecular Weight	230.47 g/mol
Synonyms	Propynoic Acid, Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Propiolate; 3-(Trimethylsilyl)-2-propynoic Acid Trimethylsilyl Ester; TMS Propiolate; Bis(TMS) Propynoate; 2-Propynoic Acid, Bis(trimethylsilyl) Ester; (Trimethylsilyl)propiolic Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Every batch of Trimethylsilyl(Trimethylsilyl)Propynoate is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous analytical testing, including GC, HPLC, and NMR, to verify identity, purity, and absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain purity and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.