Description

Tibenelast CAS NO 97852-72-7 is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the development of novel therapeutic agents, particularly in the respiratory and inflammatory disease research sectors. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting respiratory conditions.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies, especially for investigating phosphodiesterase (PDE) inhibition pathways.
• Drug Discovery & Development: Employed in preclinical research for the development of new anti-inflammatory and bronchodilator medications.
• Process Chemistry & Scale-Up: Serves as a critical raw material for process optimization and pilot-scale manufacturing of candidate drugs.
• Academic Research: Utilized in university and institutional labs for studying cellular signaling mechanisms related to asthma and COPD.

Basic Information

Product Name	Tibenelast
CAS No.	97852-72-7
Molecular Formula	C16H14N2O4S
Molecular Weight	330.36 g/mol
Synonyms	Tibenelast; 4-[(3,4-Dimethoxyphenyl)methyl]-2(1H)-quinazolinone; 4-[(3,4-Dimethoxybenzyl)-2-quinazolinone; CP-66,248; Quinazolinone derivative CP-66248
EINECS	Contact for details

Quality Control

Our Tibenelast is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.