Description

Piritramide Dihydrochloride is a potent synthetic opioid analgesic compound, primarily utilized in pharmaceutical research and development. Its significance lies in its high-affinity binding to μ-opioid receptors, making it a critical reference standard and intermediate for developing and testing new pain management therapeutics. This product is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on neuropharmacology and analgesic drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control (QC/QA) in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of specialized opioid analgesic formulations.
• Pharmacological Research: Employed in in vitro and in vivo studies to investigate opioid receptor mechanisms, efficacy, and side-effect profiles.
• Analytical Testing: Critical for calibrating equipment (HPLC, GC-MS) and conducting impurity profiling and stability studies of opioid-based medications.
• Forensic Analysis: Used as a control substance in forensic toxicology for the identification and quantification of synthetic opioids.

Basic Information

Product Name	Piritramide Dihydrochloride
CAS No.	97828-37-0
Molecular Formula	C27H34N4O2 · 2HCl
Molecular Weight	523.51 g/mol
Synonyms	Piritramide HCl; Piritramid Dihydrochloride; R-3365; Pirinitramide Dihydrochloride; 1'-(3-Cyano-3,3-diphenylpropyl)-[1,4'-bipiperidine]-4'-carboxamide Dihydrochloride; Dipidolor (brand name variant); Piritramide Dihydrochloride Salt
EINECS	Contact for details

Quality Control

Our Piritramide Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with relevant standards for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.