Description

Nalorphine-7,8-Oxide is a specialized chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of opioid antagonists and related therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in neuropharmacology and analgesic drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for novel opioid receptor modulators and antagonists.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical substances.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of morphine-derived compounds and their metabolites.
• Metabolite Studies: Acts as a model compound or synthetic analog for researching the metabolic pathways and oxidation products of nalorphine.
• Academic Research: Utilized in university and institutional labs for pharmacological experiments and educational purposes in medicinal chemistry.

Basic Information

Product Name	Nalorphine-7,8-Oxide
CAS No.	97242-25-6
Molecular Formula	C19H21NO4
Molecular Weight	327.38 g/mol
Synonyms	Nalorphine N-Oxide; 7,8-Didehydro-4,5α-epoxy-17-(2-propenyl)morphinan-3,6α,14-triol N-Oxide; N-Allylnoroxymorphone N-Oxide; N-Allyl-14-hydroxynordihydromorphinone N-Oxide; Nalorphine Oxide; Naloxone related compound (Oxide form); Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our Nalorphine-7,8-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.