Description

1,2,3,4-Tetrahydro-1-(2-Fluorophenyl)-6-Methoxy-2-Phenylisoquinoline is a complex heterocyclic organic compound featuring a tetrahydroisoquinoline core substituted with fluorophenyl and methoxy groups. This compound serves as a critical advanced pharmaceutical intermediate (API) for the research and synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Preclinical Development: Serves as a precursor for producing compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Manufacturing (CMO): Supplied to organizations providing custom synthesis and scale-up services for the pharmaceutical industry.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Item	Details
Product Name	1,2,3,4-Tetrahydro-1-(2-Fluorophenyl)-6-Methoxy-2-Phenylisoquinoline
CAS No.	97106-80-4
Molecular Formula	C22H20FNO
Molecular Weight	333.40 g/mol
Synonyms	1-(2-Fluorophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline; 6-Methoxy-2-phenyl-1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-(2-fluorophenyl)isoquinoline; 97106-80-4; 1-(2-Fluorophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline; 2-Phenyl-1-(2-fluorophenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-1-(2-Fluorophenyl)-6-Methoxy-2-Phenylisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.