Description

m-Peg2-Phosphonic Acid CAS NO 96962-41-3 is a specialized bifunctional organic compound featuring a phosphonic acid group linked to a short polyethylene glycol (PEG) spacer. This unique structure makes it a valuable intermediate for introducing hydrophilic, non-fouling properties and stable metal-chelating functionalities into target molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for applications requiring surface modification, controlled functionalization, and the development of novel drug delivery systems.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, targeted therapeutics, and bioconjugates to enhance solubility and pharmacokinetic profiles.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker for attaching drugs, dyes, or other payloads to proteins, antibodies, or nanoparticles via its phosphonic acid group.
• Surface Modification & Functionalization: Applied to coat and functionalize metal oxides (e.g., titanium, iron oxide) and other surfaces to impart hydrophilicity, prevent non-specific binding, and enable further covalent attachment.
• Metal Chelation & Coordination: Acts as a ligand for metal ions in catalysis, imaging agents (e.g., MRI contrast agents), or metal-organic frameworks (MOFs).
• Polymer & Material Science: Incorporated as a monomer or modifier to create polymers with enhanced biocompatibility, metal-binding capacity, or specific surface interactions.
• Research & Development: A key reagent in academic and industrial R&D for exploring new bio-interfaces, diagnostic assays, and advanced material composites.

Basic Information

Product Name	m-Peg2-Phosphonic Acid
CAS No.	96962-41-3
Molecular Formula	C7H17O7P
Molecular Weight	244.18 g/mol
Synonyms	2-[2-(Phosphonooxy)ethoxy]ethanol; Phosphoric acid mono[2-(2-hydroxyethoxy)ethyl] ester; (2-Hydroxyethoxy)ethyl phosphate; PEG2-phosphonic acid; mPEG2-phosphonate; HO-PEG2-OPO3H2; Ethylene glycol oligomer phosphonic acid derivative; 2-(2-Phosphonooxyethoxy)ethanol
EINECS	Contact for details

Quality Control

Our m-Peg2-Phosphonic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for active content determination, to ensure it meets precise specifications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions (e.g., nitrogen atmosphere) at a controlled room temperature (15-25°C). Keep the container sealed in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.