Description

Dl-Glutamic-2,4,4-D3 Acid is a stable isotope-labeled analog of glutamic acid, where three hydrogen atoms are replaced by deuterium at specific positions. This compound is essential as an internal standard in quantitative mass spectrometry, enabling precise and accurate measurement of glutamic acid levels in complex biological matrices. It is primarily utilized by analytical laboratories, pharmaceutical researchers, and academic institutions engaged in metabolomics, neuroscience research, and pharmacokinetic studies.

Application

• Mass Spectrometry Internal Standard: Critical for the accurate quantification of endogenous glutamic acid in LC-MS and GC-MS analyses.
• Metabolomics Research: Used as a stable isotope tracer to study metabolic pathways and flux analysis in biological systems.
• Neuroscience & Neurochemistry: Employed in research on excitatory neurotransmission, synaptic function, and neurological disorders.
• Pharmaceutical Development: Serves as a reference standard in drug metabolism and pharmacokinetics (DMPK) studies for compounds targeting glutamate pathways.
• Clinical Diagnostics: Potential use in developing assays for monitoring glutamate-related biomarkers in physiological fluids.
• Food & Nutritional Science: Applied in research analyzing glutamic acid content and umami flavor profiling in food products.

Basic Information

Product Name	Dl-Glutamic-2,4,4-D3 Acid
CAS No.	96927-56-9
Molecular Formula	C5H6D3NO4
Molecular Weight	151.14 g/mol
Synonyms	(±)-2-Aminopentanedioic-2,4,4-d3 Acid; DL-Glutamic-2,4,4-d3 Acid; Glutamic Acid-2,4,4-d3 (racemic); 2-Aminoglutaric-2,4,4-d3 Acid; (RS)-Glutamic-2,4,4-d3 Acid; 2,4,4-Trideutero-DL-glutamic Acid; NSC 169329-d3; (±)-Glutamic-2,4,4-d3 Acid
EINECS	Contact for details

Quality Control

Our Dl-Glutamic-2,4,4-D3 Acid is produced under strict quality management protocols to ensure high chemical purity and isotopic enrichment. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and analytical data is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.