Description

2,5-Dioxo-Pyrrolidine-3-Carboxylic Acid Ethyl Ester is a high-purity organic building block and heterocyclic compound of significant commercial interest. This versatile intermediate is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of N-Hydroxysuccinimide (NHS) ester derivatives, which are widely used for bioconjugation and protein labeling.
• Peptide Synthesis: Serves as a protected or activated glutamic acid derivative for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Agrochemical Development: Used as a building block for creating novel herbicides, fungicides, and plant growth regulators with specific biological activity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers, including polyimides and materials with specific degradation profiles.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) and other tools for studying enzyme function and metabolic pathways.
• Material Science: Utilized in the development of advanced organic electronic materials and liquid crystals due to its rigid, planar structure and functional handles.

Basic Information

Product Name	2,5-Dioxo-Pyrrolidine-3-Carboxylic Acid Ethyl Ester
CAS No.	96905-68-9
Molecular Formula	C7H9NO5
Molecular Weight	187.15 g/mol
Synonyms	Ethyl 2,5-dioxopyrrolidine-3-carboxylate; Ethyl 3-carboxy-2,5-pyrrolidinedione; 3-(Ethoxycarbonyl)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione-3-carboxylic acid, ethyl ester; Ethyl 3-carboxy-2,5-diketopyrrolidine; N-Hydroxysuccinimide glutamic acid ethyl ester derivative; Succinimide glutamic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2,5-Dioxo-Pyrrolidine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.