Description

Cyclobutane, 1,1-Dichloro-2-Ethynyl- (9Ci) CAS NO 96660-46-7 is a specialized halogenated cyclobutane derivative featuring both chloro and ethynyl functional groups, making it a valuable synthon in advanced organic synthesis. This compound is engineered to serve as a key building block for the development of novel molecular architectures, particularly in pharmaceutical and materials science research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and advanced material sectors for constructing complex, strained-ring systems.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those containing strained carbocyclic or heterocyclic cores.
• Agrochemical Research: Used in the development of new active ingredients with unique modes of action, leveraging its reactive ethynyl group for further functionalization.
• Material Science: Acts as a monomer or cross-linking agent in the research and development of specialty polymers and advanced organic frameworks.
• Chemical Synthesis: A versatile building block for [2+2] cycloaddition reactions and other ring-forming transformations to create complex, multi-cyclic structures.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysis, exploiting the coordination potential of the alkyne moiety.
• Academic & Industrial R&D: Employed in exploratory chemistry for the discovery of new reactions and compounds with potential commercial applications.

Basic Information

Product Name	Cyclobutane, 1,1-Dichloro-2-Ethynyl- (9Ci)
CAS No.	96660-46-7
Molecular Formula	C6H6Cl2
Molecular Weight	149.02 g/mol
Synonyms	1,1-Dichloro-2-ethynylcyclobutane; 2-Ethynyl-1,1-dichlorocyclobutane; 1,1-Dichloro-2-ethynyl-cyclobutane; 96660-46-7; 1,1-Dichloro-2-ethynylcyclobutane (9CI); Cyclobutane, 1,1-dichloro-2-ethynyl-
EINECS	Contact for details

Quality Control

Our Cyclobutane, 1,1-Dichloro-2-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.