Description

1H-Indole,5-Fluoro-1-Hydroxy- is a high-purity, fluorinated indole derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both a fluorine substituent and a hydroxyl group on the indole core, makes it a valuable synthon for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and plant growth regulators that leverage the metabolic stability imparted by the fluorine atom.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Biochemical Research: Employed as a probe or inhibitor in enzymatic studies due to its structural similarity to natural indole-based compounds.
• Organic Synthesis: A versatile building block for constructing complex heterocyclic frameworks in medicinal and process chemistry.

Basic Information

Item	Details
Product Name	1H-Indole,5-Fluoro-1-Hydroxy-
CAS No.	96631-92-4
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	5-Fluoro-1-hydroxyindole; 5-Fluoro-1H-indol-1-ol; 1-Hydroxy-5-fluoroindole; 5-Fluoroindolin-1-one (tautomer); 5-Fluoro-1-oxo-2,3-dihydro-1H-indole; 5-Fluoro-1-indolinone; 5-Fluoro-1H-indole-1-ol; 5-Fluoro-1-indolol
EINECS	Contact for details

Quality Control

Our 1H-Indole,5-Fluoro-1-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.