Description

Ablukast CAS NO 96566-25-5 is a potent and selective leukotriene receptor antagonist (LTRA) used in pharmaceutical research and development. This compound is valued for its role in modulating inflammatory pathways, particularly those involved in respiratory conditions. It is primarily utilized by pharmaceutical companies and research institutions engaged in the development of novel therapeutics for asthma, allergic rhinitis, and other inflammatory diseases.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) or intermediate in the synthesis of anti-inflammatory and anti-asthmatic medications.
• Biochemical Research: Used as a reference standard and research tool in pharmacological studies to investigate leukotriene-mediated pathways and receptor binding.
• Drug Discovery & Development: Employed in preclinical research for screening and developing new therapeutic agents targeting cysteinyl leukotriene receptors (CysLT1).
• Academic Research: Utilized in university and institutional labs for studying the mechanisms of inflammation and evaluating potential drug candidates.

Basic Information

Product Name	Ablukast
CAS No.	96566-25-5
Molecular Formula	C19H16ClNO4S2
Molecular Weight	421.92 g/mol
Synonyms	Ablukast; ONO-RS-411; ONO RS 411; 4-(4-Benzhydrylthio-3-chlorophenyl)-4-oxobutanoic acid; 4-[4-(Diphenylmethylsulfanyl)-3-chlorophenyl]-4-oxobutanoic acid; RS-411; ONO 1078 (related compound)
EINECS	Contact for details

Quality Control

Our Ablukast is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.