Description

(2R,3S)-3-(1,3-Benzodioxol-5-Yl)-3-Hydroxy-2-[1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl]Propionic Acid is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting complex biological pathways. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology industries for the production of novel therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used in stereoselective reactions to construct molecules with specific three-dimensional configurations.
• Medicinal Chemistry Research: Serves as a key scaffold in drug discovery and development programs for new therapeutic agents.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial drug manufacturing.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2R,3S)-3-(1,3-Benzodioxol-5-Yl)-3-Hydroxy-2-[1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl]Propionic Acid
CAS No.	96561-34-1
Molecular Formula	C18H13NO7
Molecular Weight	355.30 g/mol
Synonyms	(2R,3S)-3-(1,3-Benzodioxol-5-yl)-3-hydroxy-2-(1,3-dioxoisoindolin-2-yl)propanoic acid; (2R,3S)-3-(Benzo[d][1,3]dioxol-5-yl)-3-hydroxy-2-(1,3-dioxoisoindolin-2-yl)propanoic acid; 2-Phthalimido-3-hydroxy-3-(3,4-methylenedioxyphenyl)propionic acid (specifying (2R,3S) isomer); NSC 339586; A key intermediate for certain protease inhibitors.
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-(1,3-Benzodioxol-5-Yl)-3-Hydroxy-2-[1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl]Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.