Description

5-Bromo-1-(p-Toluenesulfonyl)-1H-Indole is a high-purity, functionalized indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, protected scaffold for constructing complex heterocyclic molecules, enabling efficient and selective chemical transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor modulators, and other biologically active indole-based compounds.
• Agrochemical Research: Used in the creation of new active ingredients for crop protection products, leveraging its halogen and sulfonyl functional groups for structure-activity relationship (SAR) studies.
• Organic Synthesis Reagent: Serves as a versatile precursor in cross-coupling reactions (e.g., Suzuki, Stille), nucleophilic substitutions, and other catalytic processes to introduce complex indole motifs.
• Material Science: Potential monomer or precursor for the development of specialty polymers, organic semiconductors, and functional dyes with tailored electronic properties.
• Academic & Contract Research: A valuable tool for methodological development and exploration of new reaction pathways in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	5-Bromo-1-(p-Toluenesulfonyl)-1H-Indole
CAS No.	96546-77-9
Molecular Formula	C15H12BrNO2S
Molecular Weight	350.23 g/mol
Synonyms	5-Bromo-1-tosyl-1H-indole; 1H-Indole, 5-bromo-1-[(4-methylphenyl)sulfonyl]-; 5-Bromo-1-(4-methylphenylsulfonyl)indole; 5-Bromo-1-tosylindole; 5-Bromoindole-1-tosylate; 5-Bromo-1-(p-tolylsulfonyl)indole; 5-Bromo-1-(4-toluenesulfonyl)indole; Tosyl-5-bromoindole
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-1-(p-Toluenesulfonyl)-1H-Indole is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.