Description

1-n-Amidino-1-n-Demethyl-2-Hydroxydestomycin A is a chemically modified derivative of the aminoglycoside antibiotic destomycin A, characterized by the introduction of an amidino group and a hydroxyl group. This structural modification is significant as it can alter the compound's biological activity, spectrum, and physicochemical properties, making it a valuable intermediate for pharmaceutical research and development. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel antimicrobial agents, structure-activity relationship (SAR) studies, and the development of new therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic building block for the research and development of new antibiotic and antimicrobial agents.
• Structure-Activity Relationship (SAR) Studies: Used in medicinal chemistry to understand how specific structural changes (amidino, demethyl, hydroxyl) affect biological potency and selectivity.
• Biochemical Research: Employed as a tool compound in studies targeting bacterial protein synthesis and ribosomal function.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling of related destomycin compounds.
• Veterinary Pharmaceutical Development: Investigated for potential applications in developing new treatments for animal health, given the agricultural use of related aminoglycosides.

Basic Information

Product Name	1-n-Amidino-1-n-Demethyl-2-Hydroxydestomycin A
CAS No.	96479-74-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-Hydroxydestomycin A amidine derivative; 1-N-Amidino-1-N-demethyl-2-hydroxydestomycin A; Destomycin A, 1-N-amidino-1-N-demethyl-2-hydroxy-; 2-Hydroxy-1-N-amidino-1-N-demethyldestomycin A; 96479-74-2; Amidino-demethyl-hydroxydestomycin A
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request, supporting your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under a dry inert atmosphere or in a controlled humidity environment for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.