Description

4-Androsten-17Alpha-Methyl-D3-17Beta-Ol-3-One CAS NO 96425-03-5 is a high-purity, deuterated steroid derivative, specifically a methylated and deuterated analog of androstenedione. This compound is of significant value in research and development for its use as a stable isotope-labeled internal standard in analytical chemistry, particularly in mass spectrometry. It is primarily required by pharmaceutical R&D laboratories, forensic science institutions, and specialized contract research organizations (CROs) for method development, doping control analysis, and metabolic studies.

Application

• Analytical Reference Standard: Serves as a critical internal standard in LC-MS/MS and GC-MS for the quantitative analysis of anabolic steroids and their metabolites.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to trace and quantify metabolic pathways.
• Forensic & Doping Control: Essential for laboratories conducting anti-doping tests in sports to ensure accurate identification and quantification of prohibited substances.
• Isotope Labeling Studies: Employed in biochemical research to investigate steroid hormone biosynthesis, degradation, and receptor interactions using deuterium as a tracer.
• Method Development & Validation: Provides a stable, non-interfering standard for developing and validating highly sensitive analytical methods in complex matrices.

Basic Information

Product Name	4-Androsten-17Alpha-Methyl-D3-17Beta-Ol-3-One
CAS No.	96425-03-5
Molecular Formula	C20H29D3O2
Molecular Weight	305.48 g/mol
Synonyms	17α-Methyl-androst-4-ene-3β,17β-diol-d3; 17α-Methylandrost-4-ene-3β,17β-diol-d3; 3β,17β-Dihydroxy-17α-methylandrost-4-ene-d3; Deuterated Methylandrostenediol; M1T Precursor-d3; Methyl-1-testosterone precursor-d3; 17α-Methyl-5α-androst-1-ene-3β,17β-diol-d3 (related isomer)
EINECS	Contact for details

Quality Control

Our 4-Androsten-17Alpha-Methyl-D3-17Beta-Ol-3-One is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical identity, meeting the stringent requirements of analytical laboratories. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment (D3), and related substance analysis via advanced chromatographic and spectroscopic methods. We adhere to cGMP principles where applicable to guarantee traceability, consistency, and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3, MS)	≥ 98 atom % D
Chemical Purity (Titration)	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.