Description

(Fluoromethyl)Triphenylphosphonium Tetrafluoroborate is a high-purity organophosphorus salt widely recognized as a versatile reagent in advanced organic synthesis. Its primary value lies in its role as a key precursor for generating fluoromethyl ylides, enabling the efficient introduction of fluorinated methylene groups into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is critical for modulating the biological activity and physical properties of novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for creating fluorinated analogs of active pharmaceutical ingredients (APIs) to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research & Development: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can improve lipophilicity and environmental persistence.
• Material Science: Employed in the preparation of fluorinated polymers, liquid crystals, and electronic materials to alter dielectric properties and chemical resistance.
• Wittig Olefination Reagent: Serves as a specialized Wittig reagent for the stereoselective synthesis of vinyl fluorides and fluorinated olefins, which are valuable scaffolds in medicinal chemistry.
• Fluorine Chemistry Research: A fundamental reagent in academic and industrial laboratories exploring new methodologies for C-F bond formation and fluoromethylation reactions.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value fluorinated fine chemicals and specialty additives.

Basic Information

Product Name	(Fluoromethyl)Triphenylphosphonium Tetrafluoroborate
CAS No.	96385-23-8
Molecular Formula	C20H19BF5P
Molecular Weight	396.15 g/mol
Synonyms	Fluoromethyltriphenylphosphonium Tetrafluoroborate; (Fluoromethyl)triphenylphosphonium Boron Tetrafluoride; Triphenyl(fluoromethyl)phosphonium Tetrafluoroborate; Fluoromethyl Triphenylphosphonium BF4; Fluoromethyl-TPP Tetrafluoroborate; (Fluoromethyl)-triphenylphosphonium Tetrafluoroborate Salt; Phosphonium, (fluoromethyl)triphenyl-, tetrafluoroborate(1-)
EINECS	Contact for details

Quality Control

Our (Fluoromethyl)Triphenylphosphonium Tetrafluoroborate is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.